In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in ...

Postmitotic myotubes cannot complete DNA replication following forced cell cycle reactivation. Comparative genomic hybridization and Xenopus egg extracts show that this is primarily due to a diffuse ...

Caption In the DNA fiber assay used in this study, cells labeled with IdU (green) and CldU (red) nucleotide analogs were sorted into substages of S phase before being subjected to the DNA fiber ...

In bacteria, to start DNA replication, two replisomes attach to the DNA at a set origin point and head in opposite directions along the loop of DNA, copying DNA until they meet on the other side.