Satoshi Kon's Paranoia Agent aired on Toonami in 2005 and remains Cartoon Network's scariest anime, haunting viewers with its ...

That show originally aired on Cartoon Network from 2004 to 2009. The Powerpuff Girls originally debuted on Cartoon Network in 1998 and ran for 78 episodes until it ended in 2005.

When it comes to the best Cartoon Network shows of the 2000s, many have fond memories from the era, but which series are ranked as the overall best?