Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial Circulating cytokines, hormones, and growth factors control all ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

The past decade has seen significant advances in our understanding of Hedgehog (HH) signaling pathway in various biological events. HH signaling pathway exerts its biological effects through a complex ...

Bottom-up construction of artificial cells helps elucidate the working mechanism of cells. Signal transduction from extracellular to intracellular artificial cells is essential for autonomous ...

Comparison of the simulation treatment planning of FLT and FDG PET/CT in contouring the biologic tumor volume in patients with thoracic esophageal carcinoma. A phase I/II trial of continuous hepatic ...

An international study led by a scientist at the University of Ottawa Faculty of Medicine is opening new frontiers in the ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

That’s gene editing. On paper, it is merely the rearrangement of letters. However, the road to editing genes in hopes of a therapeutic benefit is difficult to travel. Additionally, researchers want ...

Lentiviral transduction is a popular delivery platform for applications such as CAR-T cell engineering or CRISPR-Cas9 gene editing, as it can transduce both dividing and non-dividing cells and ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a ...