In in situ capturing-based spatial transcriptomics, spots of the same size and printed at fixed locations cannot precisely capture the randomly-located single cells, therefore inherently failing to ...

Research teams are analyzing how proteins work together to enable our cells to both stick and move. The marker protein paxillin is at the center of their interest. The tissue in our body can only hold ...

Cellular senescence, a hallmark of aging, can be quantified by the gene expression composite scores for the canonical senescence pathway (CSP), senescence initiating pathway (SIP), senescence response ...

Sensome, the pioneer of microsensing technology for real-time, in situ tissue analysis, today announced the publication of a study in Science Advances unveiling an innovative methodology using its ...

This finding implies that the cell nucleus can rotate even when there is no chiral orientation of the cytoskeleton on a cellular level. To confirm whether this mechanism was driving the rotation, the ...

For some, January is a time for resolutions, with the goal often tied to being fitter and healthier. And increasingly this has included a fixation on addressing aging at the cellular level, driven in ...

This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

In a comprehensive Genomic Press interview, Stanford University researcher Eric Sun reveals how machine learning is revolutionizing our understanding of brain aging at an unprecedented cellular ...

Rising temperatures disrupt human cellular stability by impairing proteostasis, altering mitochondrial function, reprogramming gene expression, and reshaping immune responses, ultimately shifting ...

Summary: Researchers cracked open the earliest cellular origins of Rett syndrome. The investigation bypassed traditional tissue-level barriers by physically separating genetically healthy and mutated ...