Long-distance gene regulation is uncommon in bacteria, and its molecular mechanisms are unclear. Using a combination of structural, biochemical and single-molecule techniques, researchers revealed ...

Plasmids –autonomously replicating DNA molecules– exhibit a broad range of replication and mobility strategies, genetic repertoires, host ranges, sizes, and copies per cell. However, the determinants ...

Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. The advance is significant ...

Bionova Scientific, an Asahi Kasei CDMO, formed a manufacturing alliance with Syenex, a genetic medicines platform company, designed to expand global access to DNA plasmids for next-generation gene ...