In a new study published in Bone Research, a team of researchers from Johns Hopkins University and colleagues, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), has ...

This week, we are going to discuss a condition that occurs after trauma and surgery as well as after traumatic injuries to the head, neck and spine. The condition? Heterotopic ossification.

The skulls of cetaceans (whales, dolphins and porpoises) are distinguished by incomplete ossification of cranial sutures during their lifetime. We suggested suture ossification may correlate with the ...

Bone regeneration requires a well-orchestrated cellular and molecular response including robust vascularization and recruitment of mesenchymal and osteogenic cells. In femoral fractures, angiogenesis ...

For patients with thoracic ossification of the posterior longitudinal ligament (T-OPLL), surgical treatment is effective for improving neurological function, quality of life (QoL), and pain management ...

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could transform treatments for bone disorders. Scientists have identified how Discoidin ...

We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva (FOP), Mrep functions as a pathogenic cell that ...