In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

G-protein-coupled receptors (GPCRs) are the largest class of membrane receptors and key drug targets. Over the past decade, extensive evidence has shown that GPCRs signal from various intracellular ...

Metabolites are essential energy sources and building blocks for biosynthetic pathways 1. Traditionally, they were mainly thought to modulate metabolic pathways by directly influencing the activity of ...

Designated areas (white circles) were irradiated with blue light at specific frequencies (indicated in the top left of each panel) to examine chemotactic aggregation. A research team led by Dr.

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Its origin from mitochondrial DNA suggests that it may function as part of a retrograde signaling system, where mitochondria ...

In wellness and research settings, peptides are often discussed in terms of outcomes like recovery, metabolism, or tissue support. But beneath those outcomes is a more fundamental process that is ...