Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have identified new inhibitors of the enzyme human 15-lipoxygenase-2 (h15-LOX-2 ...

Researchers from the Universities of Bath and Leeds (UK) have made a significant advance in the fight against malaria by uncovering a promising new potential target for drug discovery. The findings, ...

The title of this letter paraphrases a commentary recently published in your journal by Tsukamoto: “Do angiotensin-converting enzyme inhibitors not reduce the risk of pneumonia?” [1].

First-line durvalumab with arterial chemotherapy in major portal invaded hepatocellular carcinoma: The phase 2 DurHope study with biomolecular analyses. Comparative diagnostic accuracy and tumor ...

An illustration shows the structure of an inhibitor bound to the active site of membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase. An inhibitor bound to the active site of ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

Researchers at Baylor College of Medicine and collaborating institutions are challenging the traditional understanding of how cancer drugs called histone deacetylase (HDAC) inhibitors function. For ...

Treatment decision patterns post–enfortumab vedotin plus pembrolizumab in metastatic urothelial cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not ...