A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...

Using patient-derived cells and advanced imaging, researchers showed that RPGR mutations disrupt cilia coordination and ...

Researchers at The Hong Kong University of Science and Technology (HKUST) have uncovered how mutations in a specific gene can trigger a rare respiratory disease, shedding light on the critical role ...

Primary cilia are sensory organelles that coordinate numerous cellular signalling pathways during development and adulthood. Defects in ciliary assembly or function lead to a series of developmental ...

Left-right asymmetry is known to be established during early embryogenesis by a small cluster of cells termed the left-right organizer. Within this organizer, motile cilia beat rapidly to create a ...

We previously demonstrated that the inability of primary endothelial cilia to sense fluid shear stress can lead to nitric oxide (NO) deficiency and cause hypertension (HTN). Decreased biosynthesis of ...

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling. Researchers have now revealed that cilia have a specialized transport hub at ...

New structures discovered within cilia show a relationship between certain proteins and juvenile myoclonic epilepsy. The discovery sheds new light on the microstructure of cilia. Cilia are microscopic ...

New findings from a team of investigators at Johns Hopkins Medicine have ruled out a mechanism that scientists have long believed controls the number of hairlike structures, called cilia, protruding ...

Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular ...

Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour ...

Nerve cells in the brain make elaborate connections and exchange lightning-quick messages that captivate scientists. But these cells also sport simpler, hairlike protrusions called cilia. Long ...