For decades, human cancer cell lines have been indispensable models for cancer research, already replacing a significant number of animal experiments. However, the use of fetal bovine serum (FBS) in ...
Monocyte derived macrophages (MDMs) comprise a major cellular fraction of the brain metastatic breast cancer (BMBC) tumor microenvironment (TME), however, their role in BMBC growth and response to ...
Ovarian cancer (OC) poses significant treatment challenges due to late-stage diagnosis and a complex tumor microenvironment contributing to therapy resistance. We optimized a U-CUP perfusion-based ...
Let’s face it: Nobody pursues a career in science for the joy of culturing cells. But this thankless and time-intensive task is the backbone of biological research. When it’s done extremely well, the ...
Scientists have uncovered a surprising dark side to vitamin B2: it may help cancer cells stay alive. The vitamin supports a cellular shield that protects tumors from ferroptosis, a form of programmed ...
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