Farber disease (FD) is a rare autosomal recessive disease caused by mutations in the acid ceramidase gene (ASAH1). Low ceramidase activity results in the accumulation of fatty substances, mainly ...
Colorectal cancer is the third most common cancer in the Western world. Fluoropyrimidine chemotherapy with agents such as 5-fluorouracil (5-FU) is the main method of treatment, but is effective in ...
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